Isotopically Labeled Compounds
Cayman Chemical Bosentn-d4 25mg
An internal standard for the quantification of bosentan by GC- or LC-MS
Medchemexpress LLC Octanoic acid-d3 | 156779-05-4 | 99.1% | 147.23 | 50 MG
Octanoic acid-d3 (Caprylic acid-d3) is the deuterium labeled Octanoic acid. Octanoic acid is an oily liquid with a slightly unpleasant rancid taste and is used commercially in the production of esters used in perfumery and also in the manufacture of dyes. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 5-Methyluridine-d4 | 82845-85-0 | 100.0% | 262.25 | 1 MG
5-Methyluridine-d4 is a laboratory chemical intended for research use only and for the manufacture of substances. It is stable under recommended storage conditions.
- For research use only
- Not fully validated for medical applications
- Stable under recommended storage conditions
Medchemexpress LLC Carfilzomib-d8 | 1537187-53-3 | >99.0% | 728.0 g/mol | C40H49D8N5O7 | 1 MG
Carfilzomib-d8 is the octa-deuterated form of carfilzomib supplied for research and analytical use as an internal standard. It enables accurate quantification of carfilzomib in biological and pharmaceutical samples by GC- or LC-MS, with high isotopic enrichment and analytical-grade purity.
- Octa-deuterated internal standard suitable for LC- or GC-MS quantitation.
- High isotopic enrichment and purity for minimal analytical interference.
- Suitable for quantification in biological matrices and pharmacokinetic studies.
- Provided in small, pre-weighed quantities compatible with analytical workflows.
- Molecular formula C40H49D8N5O7 and formula weight 728.0 g/mol for reference.
BIOHIPPO GAL4-TAL-BSD LV
GAL4-TAL-BSD is a transcription factor reporter lentiviral vector designed to monitor transcription factor pathways in living cells This construct delivers a Firefly Luc reporter cassette together with a Blasticidin selection marker for generation of stable cell pools The vector is provided as a ready to use Lentivirus preparation pseudotyped with VSV-G for efficient gene delivery and stable genomic integration Each vial provides a nominal titer of 2x10E6 transducing units TU Typical applications include Identification of protein-protein interactions (PPI) and as a reporter in mammalian two-hybrid assay The system is suitable for use with Human/mouse and can support assay development high content screening and mechanism of action studies This product is intended for research use only and is not for diagnostic or therapeutic procedures
Medchemexpress LLC Nicorandil-d4 | 1132681-23-2 | 99.8% | 1 MG
Nicorandil-d4 (SG-75-d4) is the deuterium-labeled Nicorandil. Nicorandil (SG-75) is a potent potassium channel activator that targets vascular nucleoside diphosphate-dependent K+ channels and cardiac ATP-sensitive K+ channels (KATP). It is a nicotinamide ester with vasodilatory and cardioprotective effects, with potential use for angina and ischemic heart diseases. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Targets vascular nucleoside diphosphate-dependent K+ channels and cardiac ATP-sensitive K+ channels (KATP).
- Has vasodilatory and cardioprotective effects.
- Potential for angina and ischemic heart diseases.
Medchemexpress LLC 1-(Ethyl-d5)-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride | 99.9% | 1 MG
Lomefloxacin-d5 hydrochloride is a deuterium labeled version of lomefloxacin hydrochloride, a broad-spectrum quinolone antibiotic with antimicrobial activity. It is utilized in research for various infections, including those of the respiratory tract, genitourinary system, gastrointestinal tract, and ENT.
- Can be used as a tracer.
- Serves as an internal standard for quantitative analysis (NMR, GC-MS, LC-MS).
- Incorporates stable heavy isotopes for quantitation in drug development.
- Deuteration may affect pharmacokinetic and metabolic drug profiles.
Medchemexpress LLC N-tert-butoxycarbonyl-2-aminoacetic acid-d2 | 42492-65-9 | MFCD01074012 | 98.0% | 177.19 g·mol⁻¹ | C7H11D2NO4 | 1mL
Boc-Glycine-d2 is the deuterium labeled Boc-Glycine[1]
Medchemexpress LLC Citric acid-13C2 | 224054-26-6 | 194.11 | 1 MG
Citric acid-13C2 is the 13C-labeled Citric acid. Citric acid is a natural preservative and food tartness enhancer. It induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid causes oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. It is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Fulvestrant-d5 | 129453-61-8 | 99.66% | 611.80 | 1 MG
Fulvestrant-d5 (ICI 182780-d5) is an isotope of Fulvestrant and a potent estrogen receptor (ER) antagonist. It effectively inhibits the growth of ER-positive MCF-7 cells and induces autophagy, demonstrating antitumor efficacy. This compound serves as a valuable tool for various analytical applications.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Contains stable heavy isotopes for quantitation during drug development
Medchemexpress LLC Cabozantinib-d4 | 1802168-53-1 | 99.0% | 1 MG
Cabozantinib-d4 is deuterium labeled Cabozantinib. Cabozantinib is a potent multiple receptor tyrosine kinases (RTKs) inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50s of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Sucralose-d6 | 1459161-55-7 | 403.67 | 1 MG
Sucralose-d6 is deuterium labeled Sucralose. Sucralose (E955; Trichlorosucrose) is a non-nutritive artificial sweetener and sugar substitute. Sucralose can activate a conserved neural fasting response and thereby exerts an appetite-stimulating effect in rodents.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Trigonelline-d3 chloride (Trigonelline-d3 hydrochloride) | 6138-41-6 | 176.62 | 5 MG
Trigonelline-d3 (chloride) is the deuterium labeled Trigonelline chloride, an alkaloid found in coffee. It has potential antidiabetic, anti-HSV-1, antibacterial, and antifungal activities.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.